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This volume explores the governance and management of science, technology, and innovation (STI) in relation to innovation policy and governance systems, highlighting its goal, challenges, and opportunities. Divided into two sections, it addresses the role of governments in promoting innovation in Latin-American contexts as well as barriers and opportunities for STI governance in the region. The chapters tackle the role of institutions, innovation funding, technological trajectories, regional innovation policies, innovation ecosystems, universities, knowledge appropriation, and markets. Researchers and scholars will find an opportunity to grasp a better understanding of innovation policies in emerging economies. This interdisciplinary work presents original research on science, technology and innovation policy and governance studies in an understudied region.