NOD Mice, Kartoniert / Broschiert

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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Non-obese diabetic or NOD mice, like the Biobreeding rat, are used as an animal model for type 1 diabetes. Non-obese diabetic (NOD) mice exhibit a susceptibility to spontaneous development of automimmune insulin dependent diabetes mellitus (IDDM). The NOD strain and related strains were developed at Shionogi Research Laboratories in Aburahi, Japan by Makino and colleagues and first reported in 1980. The group developed the NOD strain by selecting cataract-prone strains. The strain was then established by inbreeding.