Gary Walsh: Biopharmaceuticals, Kartoniert / Broschiert

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Updated all-in-one guide to understanding the development and manufacture of small and large bio-based therapeutics

Biopharmaceuticals is a unique resource on biopharmaceuticals that serves as a comprehensive introduction to both the biopharmaceutical industry and its role within the global pharmaceutical industry. This new edition incorporates all major advances from the past 20 years, including the development of biosimilars, bispecific antibodies, engineered cell-based therapies, RNA-based vaccines, and genome editing techniques. Case studies and application examples demonstrate the entire value chain, from development to approval and safe manufacturing of all types of biopharmaceuticals, covering cytokines, antibodies, nucleic acid therapeutics as well as cell-based therapeutics.

Written by an accomplished instructor and textbook writer who has been working with small and large biotech companies for more than 25 years, Biopharmaceuticals covers:

• Protein structure, covering protein folding, stability, structure prediction, and post-translational modifications
• Growth factors, covering haematopoietic growth factors, granulocyte colony stimulating factors (G-CSFs), and macrophage colony-stimulating factors (M-CSFs)
• Recombinant blood products and therapeutic enzymes, covering clotting disorders, anticoagulants, thrombolytic agents, and enzymes of therapeutic value
• Hormones, covering insulin manufactured by traditional mans, engineered insulins, and Human Growth Hormone
• Product analysis, covering API characterization, purity and potency determinations, analytical methodologies, protein content, and contaminant testing

Delivering comprehensive coverage of the field, Biopharmaceuticals is an essential reference for students and professionals in biotechnology, medical biochemistry, medicinal chemistry, and pharmaceutical technology.