Difan Xiao: Genome mining and metabolic engineering of Aureobasidium pullulans NRRL 62031 for enhanced..., Kartoniert / Broschiert
Genome mining and metabolic engineering of Aureobasidium pullulans NRRL 62031 for enhanced polymalate production
Buch
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Current price: EUR 54.00
Extended return period until January 31, 2026
All products eligible for return that were purchased between December 1 and December 31, 2025, may be returned until January 31, 2026.
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(United States of America): EUR 19.90
- Publisher:
- Apprimus Verlag, 06/2025
- Binding:
- Kartoniert / Broschiert
- Language:
- Englisch
- ISBN-13:
- 9783985552887
- Item number:
- 12330589
- Volume:
- 232 Pages
- Edition number:
- 25001
- Ausgabe:
- 1. Auflage
- Weight:
- 342 g
- Format:
- 210 x 148 mm
- Thickness:
- 15 mm
- Release date:
- 24.6.2025
- Note
-
Caution: Product is not in German language
Blurb
Polymalate (PMA), a promising drug delivery system, can be produced by Aureobasidium pullulans NRRL 62031. The key genetic determinant for PMA polymerization and the primary pathway for malate synthesis were identified. Four gene knockout targets and one overexpression target were found to enhance PMA titer. Genetic insights into PMA hydrolysis were also obtained through bioinformatics. This study lays the foundation for the large-scale production of PMA and its medical applications.
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