Small Nucleolar RNA SNORA40, Kartoniert / Broschiert

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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. The small nucleolar RNA ACA40 belongs to the H/ACA family of snoRNAs and guides the pseudouridylation of 28S rRNA subunit at position U4565. snoRNA ACA40 was originally discovered using large-scale cloning by Kiss et al. (2004) from a HeLa cell extract immunoprecipitated with an anti-GAR1 antibody. It is predicted to guide the pseudouridylation of residues 28S rRNA U4546 and 18S rRNA 1174. The pseudouridylation of these residues was previously reported by Ofengand and Bakin (1997) and Maden (1990).