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of Volume I.- 1 Historical Aspects of Intracranial Aneurysms.- Early History.- The Early 1900s.- Angiography.- Early Surgical Advances.- Vertebrobasilar Aneurysms.- 2 The Incidence of Intracranial Aneurysm.- 3 Data I.- 1 General Overview.- Materials and Methods.- 2 Single Intracranial Aneurysms Occurring in Adults.- Data Base.- Data Processing.- Results.- Discussion.- 3 Multiple Intracranial Aneurysms Occurring in Adults.- Data Base and Data Processing.- Results.- Discussion.- 4 Intracranial Aneurysms Occurring in Children.- Data Base and Data Processing.- Results of the Analysis of Single Aneurysm Cases without Associated Conditions.- Results of the Analysis of Single Aneurysm Cases with Associated Conditions.- Multiple Aneurysms Occurring in Children.- Discussion.- 5 Giant Intracranial Aneurysms Occurring in Adults.- Results of the Analysis of Adult Giant Single Aneurysms.- Giant Multiple Aneurysms Occurring in Adults.- Discussion.- 6 Summary.- Adult Single Berry Aneurysms.- Adult Multiple Berry Aneurysms.- Childhood Aneurysms.- Adult Giant Aneurysms.- 4 Data II.- Tables.- 5 Signs and Symptoms I General.- Signs and Symptoms.- Classification and Grading.- Summary.- 6 Signs and Symptoms II Specific.- 1 Specific Aneurysms.- Aneurysms of the Internal Carotid Artery and Its Branches.- Aneurysms of the Middle Cerebral Artery.- Aneurysms of the Anterior Communicating Artery.- Aneurysms of the Anterior Cerebral Artery.- Aneurysms of the Basilar Artery and Its Branches.- Aneurysms of the Vertebral Artery and Its Branches.- 2 Giant Aneurysms.- Signs of Sellar / Suprasellar Tumor.- Bruit.- Convulsive Seizures.- Trigeminal Neuralgia.- Other Findings.- 7 Signs and Symptoms III Ophthalmic.- Cranial Nerves 3, 4, 5, and 6.- Cranial Nerve 2.- Summary.- 8 Secondary Complications of the Subarachnoid Hemorrhage.- Elevated Intracranial Pressure.- Hydrocephalus.- Intracranial Hematoma.- Vasospasm.- Ischemia and Infarction.- Fluid and Electrolyte Disorders.- Rebleeding.- Epileptic Seizures.- Gastrointestinal Hemorrhage.- Pulmonary Edema.- Electrocardiographic Changes.- Summary.- 9 Vasospasm I Experimental Findings.- Definitions and Background.- Experimental Designs and Procedures.- Specific Experimental Findings.- Some Experimental Therapies in Animals and Humans.- Summary.- 10 Vasospasm II Clinical Considerations.- Location and Occurrence.- Signs and Symptoms.- Tests.- Related Factors.- Treatment.- Summary.- 11 The Pathology of Intracranial Arterial Aneurysms and their Complications.- Definitions.- Fusiform Aneurysms.- Saccular Arterial Aneurysms.- Aneurysms of Inflammatory Origin.- Neoplastic (Oncotic) Aneurysms.- Traumatic Aneurysms.- Dissecting Aneurysms.- Aneurysms of the Spinal Arteries.- 12 Etiology and Pathogenesis of Intracranial Berry Aneurysms.- Distribution of Berry Aneurysms in Nature.- Anatomic Variations Associated with Berry Aneurysms.- Persistence of Vestigial Vessels.- Medial Defects or Raphes.- Disorders Associated with Berry Aneurysms.- Early Aneurysm Formation in Man.- Experimental Arterial Aneurysms.- Other Theories.- 13 Associated Conditions I.- Intracranial Arteriovenous Malformations.- Carotid Artery Stenosis.- Moyamoya Syndrome.- Brain Neoplasms.- Aortic Stenosis (Coarctation).- Polycystic Kidneys.- Connective Tissue Diseases.- Other Disease States.- Familial Aneurysms.- Pregnancy.- 14 Associated Conditions II.- Infection: Mycotic Aneurysms.- Syphilitic Aneurysms.- Oncotic Aneurysms.- Traumatic Aneurysms.- Summary.- 15 Variations in Cerebrovascular Anatomy.- 1 Introduction.- 2 Embryology of the Cranial Arteries.- 3 Carotid-Basilar Anastomoses.- Primitive Trigeminal Arteries.- Primitive Otic Arteries.- Primitive Hypoglossal Arteries.- Variants of Primitive Trigeminal, Otic, and Hypoglossal Arteries.- 4 Carotid-Vertebral Anastomoses: The Proatlantal Intersegmental Arteries.- Embryology.- Anatomy and Angiographic Description.- Variant of Proatlantal Intersegmental Arteries.- Collateral Circulation.- 5 Aplasia of the Internal
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Professor Fox has undertaken the monumental In his Preface, Dr. Fox has quoted Cannon task of compiling the available data on intracra and Rosenblueth in questioning where to stop nial arterial aneurysms. The magnitude and ex the record. One can only document progress tent of the undertaking attest to the tremen to date-and certainly the advances in this field dous amount of information which has are noteworthy-and then make some cau accumulated in the past few decades and to tious predictions for the future. They have cor the accelerated pace at which the field has ex rectly made note that the overall morbidity panded, particularly since the end of World and mortality of these aneurysm patients re War II. mains unacceptably high, largely as a result of Our heritage can be traced to many sources, the secondary complications of the subarach among whom should be mentioned such nota noid hemorrhage itself. More attention should bles as Willis, Quincke, Blackall, Moniz, Dott, be directed in the future to the recognition of Dandy, Hounsfield, and others. The modern era those patients with unruptured aneurysms and includes a number of investigators and clini those with minimal bleeds. Hopefully infor cians, some of whom have contributed to this mation will be forthcoming as to which indi magnificent tome. The bibliography of over viduals are at risk because of some unusual con 4000 references represents the increasing in genital, metabolic, or acquired defect.
