Klappentext

Genetics and Epigenetics of Genitourinary Diseases aims to provide a comprehensive collection of data on genetics and epigenetics in almost all genitourinary diseases for researchers, clinicians and graduate students. It discusses several genetic and epigenetic changes like DNA methylation, mutations, Single Nucleotide Polymorphisms (SNPs), DNA rearrangements, chromosomal remodeling, MSI (Microsatellite Instability) and Chromosomal Instability (CIN) in genitourinary cancers. It is split into 15 chapters, beginning with the importance of genetics and epigenetics in genitourinary diseases. It then goes on to cover genetic and epigenetics of various diseases and tumors. Certain chapters present novel techniques of Next-Generation Sequencing (NGS). Furthermore, RNA-Seq is discussed as a sequencing technique that uses NGS to reveal the presence and quantity of RNA in a biological sample. This book is a valuable resource for researchers, practitioners and students in genetics and epigenetics that want to broaden their understanding of the field.