Sesquiterpene Lactones
Sesquiterpene Lactones
Buch
- Advances in their Chemistry and Biological Aspects
- Herausgeber: Virginia Susana Martino, Valeria Patricia Sülsen
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EUR 142,37**
EUR 109,51*
- Springer International Publishing, 06/2018
- Einband: Gebunden, HC runder Rücken kaschiert
- Sprache: Englisch
- ISBN-13: 9783319782737
- Bestellnummer: 8217380
- Umfang: 396 Seiten
- Nummer der Auflage: 18001
- Auflage: 1st ed. 2018
- Gewicht: 758 g
- Maße: 241 x 160 mm
- Stärke: 27 mm
- Erscheinungstermin: 20.6.2018
Achtung: Artikel ist nicht in deutscher Sprache!
Weitere Ausgaben von Sesquiterpene Lactones
Klappentext
This book addresses chemical and biological aspects related to sesquiterpene lactones (STLs). Experts in different fields have been invited to contribute on this class of compound's chemistry, isolation and identification, biological activities (antibacterial, antifungal, antiviral, antitrypanosomal, antileishmanial, antiplasmodial, antiproliferative and antiinflammatory), synthesis, biosynthesis, derivatization and QSAR analysis. Taxonomic and chemotaxonomic aspects related to the Asteraceae family are also contributed. The book begins by describing the chemical characteristics of STLs, their classification in different skeleton types, synthesis, distribution in nature and their most important biological properties. An overview of the group's main representatives, based on their importance for human health, as well as an update of the most recently isolated STLs, follow. The authors also provide an overview of the most common methods described in the literature for the extraction, purification, identification and structure elucidation of STLs, while also highlighting more recently developed methods.Furthermore, experts in the field provide an in-depth discussion of the most commonly employed in vitro and in vivo antiprotozoal assays against the different stages of parasites, as well as STLs' properties as anticancer agents in numerous cancer cell lines and animal models. Lastly, the book presents examples of the in vitro and in vivo activity of STLs and their mechanism of antiprotozoal action, together with an analysis of ultrastructural alterations, observed using TEM techniques. The book is aimed at scientists working on natural products: both those investigating this particular group of compounds and those who wish to further explore its potential as new drugs for medical conditions such as protozoal diseases and cancer.