Inhaltsangabe

General Aspects of Dendritic Cell Biology, Functions, and Clinical Application.- Dendritic Cell Biology: Subset Heterogeneity and Functional Plasticity.- Dendritic Cells and Their Role in Linking Innate and Adaptive Immune Responses.- Dendritic Cell and Pathogen Interactions in the Subversion of Protective Immunity.- Dendritic Cells as Keepers of Peripheral Tolerance.- Adjuvants, Dendritic Cells, and Cytokines: Strategies for Enhancing Vaccine Efficacy.- Ex Vivo Generated Dendritic Cells for ClinicalTrials versus In Vivo Targeting to Dendritic Cells: Critical Issues.- General Aspects of the Pathogenesis and Immune Response to HIV-1 Infection.- Immunopathogenesis of HIV Infection.- Innate Cellular Immune Responses in HIV Infection.- Adaptative Immune Responses in HIV-1 Infection.- Dendritic Cells and HIV Interactions and Their Role in Pathogenesis and Immunity.- Binding and Uptake of HIV by Dendritic Cellsand Transfer to T Lymphocytes: Implicationsfor Pathogenesis.- Loss, Infection, and Dysfunction of Dendritic Cells in HIV Infection.- HIV Exploitation of DC Biology to Subvertthe Host Immune Response.- Cross-Presentation by Dendritic Cells: Rolein HIV Immunity and Pathogenesis.- Immunotherapy of HIV Infection: Dendritic Cells as Targets and Tools.

Klappentext

Dendritic cells play the most vital part in inducing anti-viral immune responses in HIV and AIDS among many other viruses. Research on dendritic cells (DCs) is emerging as a fundamental aspect for the comprehension of the mechanisms underlying the pathogenesis of viral diseases. This volume focuses on the role of DCs in the pathogenesis and immunity of HIV-1 infection. It is the only comprehensive volume on pathogenesis and immunity of Dendritic Cells that also focuses on HIV.